Indoor air pollution has emerged as a major threat to human health worldwide that needs to be dealt urgently.The present review is an effort to overview the different indoor air pollutants (CO2, volatile organic compounds (VOCs) like formaldehyde, benzene, nitrous oxide, trichloroethylene, fluorine, ammonia, radon, aldehyde, hydrocarbons etc.) thei
Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation
Abstract Background The PI3K/AKT pathway is activated through PIK3CA or AKT1 mutations and PTEN loss in breast cancer.We conducted a phase II trial with an allosteric AKT inhibitor MK-2206 in patients with advanced breast cancer who had tumors with PIK3CA/AKT1 mutations and/or PTEN loss/mutation.Methods The primary endpoint was objective response r
DIGITAL SOLUTION FOR FAST EVALUATION OF THE POWER FACTOR IN POWER NETWORKS
Power quality evaluation involves measurements and determinations of some power quality indicators.One of these indicators is represented by the power factor.The importance of mcdsp apb 8 the power factor as an indicator of power quality, both theoretical and practical, implies its determination or direct measurement as a necessity, especially in i
Giant-cell tumor of bone: treatment options and role of denosumab
Arun S Singh,1 Neal S Chawla,2 Sant P Chawla2 1Sarcoma Service, Division of Hematology/Oncology, University of California, Los Angeles, 2Sarcoma Oncology Center, Santa Monica, CA, USA Abstract: Giant-cell tumor of bone is a rare, locally aggressive tumor that typically occurs in the bones of skeletally mature young adults in their second to fourth
Vehicle trajectory at curved sections of two-lane mountain roads: a field study under natural driving conditions
Abstract Purpose The trajectory of a vehicle is comprehensively affected by the interactions between the vehicle, the driving behavior, and the road environment.High-risk driving behaviors and accident-prone road sections can be identified based on the relationship between the trajectory and road geometry.Previous related studies mostly focused on